Inflammasomes are multimeric cytosolic protein complexes found in various cells, including macrophages, neutrophils, dendritic cells (DCs), and cardiomyocytes1. Among them, the NLRP3 (nucleotide-bi...

Bakuchiol is a natural plant compound extracted from the seeds of the leguminous plant Psoralea corylifolia. It belongs to the class of isoprenoid phenolic terpenes and accounts for over 60% o...

Wound healing is characterized by cellular and molecular complex events, consisting of three phases–inflammatory, proliferative and remodelling–, and involves cell division, reepithelialization, ne...

Heart failure is a major global health issue characterized by significant morbidity and mortality . Cardiac remodeling, which involves myocardial hypertrophy and fibrosis, is a key f...

NADH and Disease NADH, a critical molecule in cellular metabolism and energy production, plays a central role in various diseases. Below, I will explore how NADH impacts neurodegenerative dis...

Ability to Cross the Blood-brain Barrier It has been reported that chlorogenic acid or its metabolites may cross the blood-brain barrier and exert neuroprotective effects on brain...

Primary Functions of FISETIN HYDRATE 68% clearance of senescent cells. By reducing the accumulation of senescent cells, it lowers the release of pro-inflammatory cytokines (e.g., IL-...

Carnosic acid, a phenolic diterpene naturally found in Lamiaceae plants such as rosemary and sage, has garnered significant attention for its broad spectrum of biological activities. This compound,...